2023/12-至今 中山大学附属第五医院 副研究员

2023/03-2023/12 中山大学附属第五医院 助理研究员

2020/09-2023/03 中山大学附属第五医院 博士后

2014/09-2020/07厦门大学 博士（硕博连读）

1. 放射性分子探针设计、合成与标记

2. 肿瘤、炎症相关疾病PET/SPECT成像研究

3. 放射性药物转化临床前研究

在研科研项目：

国家自然科学基金青年科学基金项目, 82202207, 新型STING靶向PET探针用于三阴性乳腺癌免疫治疗疗效预测与评估的研究, 2023-01-01至2025-12-30, 主持

近期代表性文章

1. Duo Xu^#, Xin Lu#, Fan Yang#, Zebo Jiang, Shirui Yang, Lei Bi, Jiani Liu, Hong Shan*, Dan Li. STING-targeted PET tracer for early assessment of tumor immunogenicity in colorectal cancer after chemotherapy. European Journal of Nuclear Medicine and Molecular Imaging. 51(3):641-655(2024)

2. Fan Yang#, Mengzhu Li#, Duo Xu^#, Zebo Jiang#, Hailong Jiang, Yitai Xiao, Chaoming Mei, Meilin Yang, Congmin Chen, Bin Zhou, Bailiang He*, Hong Shan*, Pengfei Pang*, Dan Li*. "Inhibition of JNK/c-Jun-ATF2 overcomes cisplatin resistance in liver cancer through down-regulating galectin-1." International Journal of Biological Sciences. 19(8):2366-2381(2023)

3. Zhou Ye#, Xin Lu#, Manman Zhu#, Lei Bi, Fan Yang, Bin Zhou*, Duo Xu*, Lan Yao*. STING-Targeted PET Imaging for Specific Detection and Therapeutic Monitoring of Myocarditis. Molecular Pharmaceutics.(2024)

4. Duo Xu^#, Fan Yang^#, Jiayao Chen^#, Tianxing Zhu, Fen Wang, Yitai Xiao, Zibin Liang, Lei Bi, Guolong Huang, Zebo Jiang*, Hong Shan*, Dan Li*. Novel STING-targeted PET radiotracer for alert and therapeutic evaluation of acute lung injury, Acta Pharmaceutica Sinica B. 2022. https://doi.org/10.1016/j.apsb.2022.12.017.

5. Jiayao Chen^#, Jiani Liu^#, Duo Xu^#, Junfeng Liu^#, Xiaojun Chen, Shuai Yang, Pan Yin, Zebo Jiang, Chaoming Mei, Xiaoting Zhang, Lizhu Wang, Ke Zhang, Bin Zhou*, Hong Shan*, Dan Li*, Pengfei Pang*. Lu3+-based nanoprobe for Virtual Non-Contrast CT imaging of hepatocellular carcinoma,Journal of Controlled Release, 2022, Sep;349:327-337.

6. Yitai Xiao^#, Chaoming Mei^#, Duo Xu^#, Fan Yang, Meilin Yang, Lei Bi, Junjie Mao*, Pengfei Pang*, Dan Li*, Identification of a CEACAM5 targeted nanobody for positron emission tomography imaging and near-infrared fluorescence imaging of colorectal cancer, European Journal of Nuclear Medicine and Molecular Imaging. 2023. https://doi.org/10.1007/s00259-023-06183-7

7. Duo Xu^#, Xiaoru Lin^#, Xinying Zeng^#,Xuejun Wen, Jingchao Li, Yesen Li, Jinxiong Huang, Xiaoyuan Chen, Zhide Guo*, Xianzhong Zhang*. Radioiodinated 4-(p-Iodophenyl) Butanoic Acid-Modified Estradiol Derivative for ER Targeting SPECT Imaging, Analytical Chemistry. 2021, 93(41):13998-14006.

8. Zhi Zhang^#, Duo Xu^#, Jianyang Fang^#, Dai Wang^#, Jie Zeng, Xiaodong Liu,  Shouqiang Hong, Yunxin Xue, Xianzhong Zhang* and Xilin Zhao*. In Situ Live Imaging of Gut Microbiota, mSphere. 2021, 6 (5): e00545-21.

9. Duo Xu#, Chenyu Peng, Fei Gao, Zhide Guo, Rongqiang Zhuang, Xinhui Su, Xianzhong Zhang*. Radioiodinated Estradiol Dimer for Targeting Estrogen Receptor-Expressing Breast Cancer, Chemical Biology & Drug Design. 2020, 96(6):1332-1340.

10. Duo Xu#, Rongqiang Zhuang, Linyi You, Zhide Guo, Xiangyu Wang, Chenyu Peng, Deliang Zhang, Pu Zhang,Hua Wu, Weimin Pan, Xianzhong Zhang*. 18F-Labeled Estradiol Derivative for Targeting Estrogen Receptor-Expressing Breast Cancer, Nuclear Medicine and Biology. 2018, 59: 48-55.