姓名:秦静波
职称: 助理研究员 电子邮件: [email protected] 通讯地址: 珠海市香洲区梅华东路52号中山大学附属第五医院分子影像中心
职称: 助理研究员 电子邮件: [email protected] 通讯地址: 珠海市香洲区梅华东路52号中山大学附属第五医院分子影像中心
2020/08-2023/03,厦门大学,博士后
2014/09-2020/06,厦门大学,化学生物学,博士(硕博连读)
2010/09-2014/06,中国药科大学,药学,学士
1. 靶向核受体,激酶小分子药物的设计合成及作用机制研究
2. 细胞器靶向递送系统的研究
3. 药物筛选与转化研究
1. 国家自然科学基金青年科学基金项目, 22207093, 靶向核受体 Nur77 并诱导 KRAS 突变结直肠癌巨泡式死亡的小分子化合物的发现及作用机制研究, 2023-01-01至2025-12-30, 主持
1. Jingbo Qin#, Xiaohui Chen#, Weihao Liu#, Jun Chen, Weirong Liu, Yongzhen Xia, Zhehui Li, Mingyu Li, Shaojuan Wang, Quan Yuan, Yingkun Qiu *, Zhen Wu *, Meijuan Fang *. Discovery of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives as novel anti-cancer agents targeting Nur77. European Journal of Medicinal Chemistry, 2022, 244, 114849.
2. Jingbo Qin#, Ningqiang Gong#, Zhihuan Liao, Shouwen Zhang, Peter Timashev, Shuaidong Huo* Xing-Jie Liang* Recent Progress in Mitochondria-Targeting-Based Nanotechnology for Cancer Treatment. Nanoscale 2021, 13, 7108.
3. Jingbo Qin#, Jie Liu#, Chunxiao Wu, Jianwen Xu, Bowen Tang, Kaiqiang Guo, Xiaohui Chen, Weihao Liu, Tong Wu, Hu Zhou*, Meijuan Fang*, Zhen Wu*. Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxam -ide/carbothioamide derivatives as novel RXRα antagonists. Journal of Enzyme Inhibition and Medicinal Chemistry 2020, 35 (1), 880-896.